1. When we spike, our mitochondria become overwhelmed and start producing chemicals called free radicals. Free radicals harm our cells, mutate our DNA, lead to oxidative stress and inflammation. Sweet spikes do this even more than starchy spikes. Inflammation is the root cause of most diseases. Three out of five people will die of an inflammation-based disease
2. When we spike, our body ages. Each glucose spike leads to glycation, which is the process of aging of our body. Glycation leads to many age-related issues, from cataracts to Alzheimer’s. When we slow down glycation, we live a longer, healthier life.
3. When we spike, insulin gets released, and excess glucose gets stored as fat. Fructose gets stored only as fat.
Weight loss is always preceded by insulin levels lowering. Lowering insulin is key to weight loss.
Biplab Giri et al., “Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: an update on glucose toxicity,” Biomedicine & pharmacotherapy, no. 107 (2018): 306-328,
Masamitsu Ichihashi et al., “Glycation stress and photo-aging in skin,” Anti-Aging Medicine 8, no. 3 (2011): 23-29,